We are the Laboratory for Mass Spectrometry and Metabolomics, affiliated with Interdisciplinary Research Center on Biology and Chemistry (IRCBC), Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences (CAS).
Metabolites, the chemical entities that are transformed during metabolism, provide a functional readout of cellular biochemistry. With mass spectrometry based metabolomics technique, thousands of metabolites can now be quantitatively measured from minimal amounts of biological material, which…
The metabolome includes not just known but also unknown metabolites; however, metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility – mass spectrometry (IM-MS) has emerged as a promising technology by providing multi-dimensional characterizations of metabolites